Effect of prostaglandin F-2 on steroidogenesis by porcine corpora lutea

Effect of a specific aromatase inhibitor on oestradiol secretion by porcine corpora lutea at various stages of the luteal phase.

The present study was undertaken to investigate the aromatization capability of pig corpora lutea at different stages of the luteal phase using the nonsteroidal aromatase inhibitor CGS 16949A. Luteal cells were collected during early (0-2 days after ovulation), mid- (7-10 days after ovulation) and late (13-16 days after ovulation) luteal phase. Cells were incubated either with or without 10(-7)...

Effect of continuous intrauterine administration of prostaglandin E2 on life span of corpora lutea of nonpregnant ewes.

The antiluteolytic effect of prostaglandin (PG) E2 was tested in two experiments. In experiment I, seven nonpregnant ewes that had ovulated bilaterally, were laparotomized on day-11 postestrus. Uterine horns were isolated by ligatures between the internal and external bifurcations and around blood vessels in the intercornual area. An Alzet TM minipump (25 • 6.5 ram) containing PGE2 (delivery ra...

Effect of aspirin, flurbiprofen and indomethacin on porcine testicular steroidogenesis.

Non-steroidal anti-inflammatory drugs (NSAIDS), of which aspirin, flurbiprofen and indomethacin are examples, exert anti-inflammatory as well as antipyretic and analgesic effects. In addition, aspirin and indomethacin have been reported to cause a reduction in fertility of male rats when applied locally to the epididymis [l ,2]. Another study shows that flurbiprofen dows not impair fertility wh...

Effect of LH on prostaglandin F2alpha and prostaglandin E2 secretion by cultured porcine endometrial cells.

LH appears to be a potent stimulator of the release of endometrial prostaglandins (PGs) in the pig. The aim of the present studies was to examine the effect of LH on PGF2alpha and PGE2 secretion by cultured porcine endometrial cells on days 10-12 and 14-16 of the oestrous cycle and to compare its action with oxytocin. A time-dependent effect of LH (10 ng/ml) on PGF2alpha release from luminal ep...

In vitro synthesis of progesterone by swine corpora lutea.